How is hATTR amyloidosis passed down?

Hereditary ATTR (hATTR) amyloidosis is an autosomal dominant condition—meaning each child of one parent with hATTR amyloidosis has a 50% chance of inheriting a gene change (or mutation) that causes the condition.

How hATTR amyloidosis is inherited

When one parent carries an autosomal dominant mutation, each child will have a 50% chance of inheriting a gene change (or mutation) that may cause this condition

A family member may inherit the transthyretin (TTR) gene change but having the mutation does not necessarily mean that he or she will develop hATTR amyloidosis.

Download the Family Health Tree tool to help you keep track of your family history and have a productive conversation with your doctor.


“We’re a very close family, we share everything…if there’s a new symptom, we all want to know about it.”

SANDIE, living with hATTR amyloidosis