How is hATTR amyloidosis passed down?
Hereditary ATTR (hATTR) amyloidosis is an autosomal dominant condition—meaning each child of one parent with hATTR amyloidosis has a 50% chance of inheriting a genetic variant, or change, that causes the condition. This change in the transthyretin (TTR) gene may also be referred to as a mutation.
How hATTR amyloidosis is inherited
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A family member may inherit the TTR gene variant, but having the variant does not necessarily mean that they will develop hATTR amyloidosis.
“We’re a very close family, we share everything… if there’s a new symptom, we all want to know about it.”
Genetic Counseling & Testing Guide
An overview of the genetic testing process for hATTR amyloidosis
Alnylam Pharmaceuticals sponsors no-charge, third-party genetic counseling and testing for individuals at risk for hATTR amyloidosis
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